Divergent functions of murine Pax3 and Pax7 in limb muscle development
نویسندگان
چکیده
منابع مشابه
Divergent functions of murine Pax3 and Pax7 in limb muscle development.
Pax genes encode evolutionarily conserved transcription factors that play critical roles in development. Pax3 and Pax7 constitute one of the four Pax subfamilies. Despite partially overlapping expression domains, mouse mutations for Pax3 and Pax7 have very different consequences. To investigate the mechanism of these contrasting phenotypes, we replaced Pax3 by Pax7 by using gene targeting in th...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2004
ISSN: 0890-9369
DOI: 10.1101/gad.301004